Abstract
Summary
Closed loops of rat jejunum in vivo have been used to study the absorption of oleic acid from nonmicellar and micellar taurocholate solutions and compared with that from micellar solutions of a nonionic detergent Pluronic Acid F 68. (a) Absorption from 15 mM taurocholate was greater than from 1 mM taurocholate over a range of oleic acid concentrations. (b). Absorption of oleic acid was proportional to its total and not its micellar concentration. (c) Pluronic acid micelles were as efficient as taurocholate micelles in promoting absorption from a 10 mM oleic acid solution but had no advantage over a nonmicellar solution at low oleic acid concentration 0.1 mM.
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