Abstract
Summary
Cystic fibrosis (CF) is characterized by exocrine hyperexcretion of sodium and calcium, and several studies have suggested abnormalities of these transport functions in the CF erythrocyte. The present study analyzed the functions of the sodiumpotassium ion exchange pump and the calcium extrusion pump of the erythrocytes of CF patients and found them to be equivalent to those of paired age and sex-matched normals, therefore, no evidence could be found to support a primary genetic defect in the CF erythrocyte.
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