Abstract
Summary
Intestinal lymph was collected from both normal and hypothalamus-injured rats given 3H-cholesterol or 3H-tripalmitin. It was found that chylomicronous cholesterol obtained from the hypothalamus-injured rat was removed from the blood and accumulated in the liver of the normal rat at the same rate as chylomicronous cholesterol collected from normal rats. However, the liver of the hypothalamus-lesioned rat removed normal chylomicronous cholesterol from plasma at a much slower rate than the liver of the normal rat. Chylomicronous triglyceride, however, was removed from plasma at a normal rate by the lesioned rat.
The heparin-induced lipoprotein-lipase activity of the plasma of hypothalamus-injured rats was significantly greater than that of the plasma of normal rats.
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