Abstract
Summary
Cutaneous basophil hypersensitivity was elicited with particulate antigens consisting of egg albumin coupled to formalinized sheep red blood cells and sheep red blood cells themselves. By observation of these visible markers, it could be seen that basophils appeared predominantly in the superficial dermis while the antigen was engulfed by macrophages in the deeper dermis.
The absence of contact between basophils and particulate antigen suggests that they are not primarily phagocytic in function and appear in response to chemotactic substances released from other cells.
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