Abstract
Summary
The plasmas of man and rhesus monkey contain a protein which oxidatively deaminates histamine, but not putrescine, at near physiological pH. Purified ceruloplasmin also gives this histaminase reaction. It migrates as a distinct zone in acrylamide disc electrophoresis except when complexed with anti-ceruloplasmin, indicating its identity with that copper-bearing protein. It is not yet established whether or not the histaminase activity of ceruloplasmin represents all or only part of the histaminase activity of plasma.
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