Abstract
Summary
Single threshold stimuli were delivered to the endocardium during early diastole in 11 dogs hourly following multistage balloon occlusion of the left anterior descending coronary artery. RVR could be evoked in all but one animal with a mean appearance time of 3.7 hr after coronary occlusion and preceding onset of spontaneous VT by an average of 2.5 hr. The RVR phenomenon may be helpful in unmasking electrical instability in the presence of coronary heart disease and in providing a simple technique for studying the effects of various interventions on the altered electrophysiologic properties of the ischemic heart.
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