Abstract
Summary
Basal serum immunoreactive insulin (IRI) levels fell promptly and in parallel with the decline observed in circulating glucose levels when alcohol was administered intravenously to fasting man. Hypoglycemia and the decrease in basal insulin secretion were associated with an initial transient increment in growth hormone levels and sustained lipolysis manifested by increased free fatty acid, glycerol and acetoacetate concentrations. These findings may result from activation of the sympathetic nervous system which is known to be operative in other hypoglycemic states.
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