Abstract
Summary
The ERC differentiation-inducing and the ERC proliferation-stimulating effects of 5 erythropoietin preparations were examined to determine whether the two effects were exerted by one or two biological entities. The Ep preparations included human and sheep Ep and ranged in purity from 161 to 0.38 units/mg. Injections at 4 dose levels in Myleran-suppressed mice failed to reveal any differences in the capability of the 5 preparations to stimulate ERC proliferation indicating that the two effects are very likely exerted by the same hormone.
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