Skin-Sensitizing Antibodies in Schistosoma mansoni Infected Baboons: Evidence for the Presence of Two Types 1

Abstract

Summary

Both short-term and long-term skin-sensitizing antibodies are present in the serum of baboons infected with the human parasite, Schistosoma mansoni. The two types were separated by ion exchange chromatography; a molecular size difference was indicated by gel filtration. Both types are heat stable at 56°, although not at 60°, for 4 hr, and both are inactivated by reduction and alkylation.