Abstract
Summary
Rat kidney mitochondria, incubated under aerobic or anaerobic conditions, catalyzed the reductive carboxylation of α-oxoglutarate. The rate of citrate accumulation was found to be an acceptable index of the rate of carboxylation. The projected maximal rate of the carboxylation which could occur in rat kidney was found to be 0.34 μmoles of α-oxoglutarate consumed/g of kidney/min.
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