Abstract
Summary
The results of this study indicate that physical training causes an adaptive increase in epinephrine-stimulated fatty acid mobilization potential in adipose tissue of rested animals. Exhaustion caused an increase in ESL activity of similar magnitude in untrained animals. The exercise effect was not additive with the training effect when trained animals were exercised or exhausted.
Lipoprotein lipase was unaffected by training and increased in heart and muscle of untrained animals following exhaustion. Trained animals exhibited a similar but smaller trend toward increased LPL activity with exercise or exhaustion.
Taken together, the results of this study are compatible with the concept that exercise increases lipolysis in adipose tissue and LPL mediated triglyceride fatty acid uptake by muscular tissues. Physical training appeared to increase the responsiveness of adipose tissue to adrenergic stimulation. An increased adipokinetic response by adipose tissue of trained animals would be compatible with the observation in this (33) and other studies (34-35) that training increases the capacity of muscular tissue for fatty acid oxidation.
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