Abstract
Summary
Ten anesthetized dogs were used to compare the hemodynamic responses to bilateral common carotid occlusion with that produced by occlusion of the brachiocephalic artery. Arterial blood pressure, heart rate, cardiac output minus coronary flow, femoral artery flow, total peripheral resistance, and hind limb vascular resistance were measured following occlusion of both common carotid arteries and following occlusion of the brachiocephalic artery. The mean values obtained for these six variables were compared using a paired t test. No significant difference was demonstrated between the values obtained using these two different experimental procedures for producing endosinusal hypotension. It can be concluded that the occlusion of the brachiocephalic artery may be used in experiments in which endosinusal hypotension has to be produced but where the occlusion of the common carotid arteries becomes impractical.
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