Abstract
Summary
Chicken antisera prepared against recombinants possessing the hemagglutinin (H3) and the neuraminidase (N2) of the A/Hong Kong/8/68 (H3N2) strains were fractionated and the homologous and heterologous [A/Japan/305/57 (H2N2)] antibody activity of the 2 major immunoglobulin classes (IgG and IgM) was determined. Homologous hemagglutination inhibition (HI) and neuraminidase inhibition (NI) titers of whole sera were found to be predominantly IgG. Heterologous HI and NI titers of whole sera were associated with IgG, IgM, or both.
The authors thank Mrs. Judy Galphin for her technical assistance.
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