Abstract
Summary
Data are presented to indicate that dexamethasone administration to rats produces dramatic changes in the circadian distribution of mitotic activity. They also indicate that the type of response observed is related to the time of the day (circadian system phase) of dexamethasone administration. Thus, either depression, relative synchronization or the establishment of a 48 hr mitotic rhythm were observed, following the administration of the steroid at 0700, 1500 and 2300 hr of the day, respectively.
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