Abstract
Summary
An inhibition of HSV DNA synthesis was observed in infected RK cells following treatment with the carcinogenic polycyclic aromatic hydrocarbon, DMBA. No such effect was observed in replicate cultures treated with the related but noncarcinogenic chemical, anthracene. The compounds were without cytocidal effects in the experimental system employed at the concentrations tested.
This investigation was supported in part by Public Health Service Research Grant No. CA-11647 from the National Cancer Institute and under Contract No. 70-2024 within the Special Virus Cancer Program of the National Cancer Institute, National Institutes of Health, U.S. Public Health Service.
Get full access to this article
View all access options for this article.