Abstract
Summary
Pulmonary surface area was significantly reduced in rats chronically exposed to low levels of carbon particulates (545 μg/m3, μ 193 SD) for 9 months. The decrease in surface area was much more pronounced at lower lung volumes. The suggestion is made that the reduction in lung surface area is related to terminal airway obstruction.
Thanks are extended to Mary Lou Eskew, Ronald Perrone and Anthony Wisbith for their technical assistance (CAES Publ. No. 217–72.)
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