Abstract
Summary
Hemoglobin polymorphism in the Barbary sheep is reviewed. Electrophoretic, chromatographic, and limited structural analyses have demonstrated that during blood-loss anemia Hb-B of this animal species is replaced by another type, termed Hb-C, whereas a Hb-C like variant, termed Hb-C(na) and present in certain nonanemic Barbary sheep, cannot be replaced when the animal is made severely anemic. Possible genetic mechanisms responsible for these phenomena are discussed.
The authors thank Mr. Jerry Collins and his staff for technical assistance, Mr. Ralph S. Yohe for his interest in this study, and Dr. Mary Jo Harris for helpful discussions.
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