Locomotor Activity of Various Types of Genetically Obese Mice

Abstract

Summary

Locomotor activity of mice was not affected by age up to 10 months. Mice of the VY/Wf and YS/ChWf strains were more active than mice of the C57BL/6J and C57BL/KsJ strains. Locomotor activity of ob/ob and db/db mice decreased significantly after these mice became corpulent. This is not the case for A^vy/a, A^y/a and NZO mice. Before they became corpulent, none of the mice genetically destined to become obese were less active than normal mice.

The authors are indebted to Professor James Ashmore, Chairman, Department of Pharmacology, Indiana University, School of Medicine, for the use of the activity cages.