Abstract
Summary
Histamine, serotonin, brady-kinin and the mast cell damaging enzyme, horseradish peroxidase, when delivered to the kidney by various routes, failed to cause venular leakage of intravenously injected colloidal carbon within the renal parenchyma. This finding was accompanied by typical venular leakage in the peripelvic, periureteral and pericystic fat and submucosa. Failure of parenchymal renal vessels to respond to vasoactive substances is probably the result of some functional or structural peculiarity of the renal microvasculature.
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