Abstract
Summary
Aerobically oxidized cellulose (AOC) accelerates clotting time of whole blood from human, rabbit and rat in siliconized tubes. Studies of its effect on the clotting sequence of recalcified human plasma show that AOC may activate the Hageman and PTA factors in a manner similar to glass surface. Heparin inhibition of clotting of recalcified plasma was effectively reversed by AOC. This may be due to an inhibitor-metabolite relationship between heparin and AOC.
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