Abstract
Summary
Mestranol in a wide range of concentrations has no direct effect upon triglyceride release from livers obtained from normal rats. The hypertriglyceridemia seen with mestranol, probably results from a stimulation by the steroid of the release of various endocrine factors which in turn may stimulate the liver to release more trigly-ceride.
This investigation was supported in part by Grant GRS FLU362-09 and TO1 AM05670-01DM from the National Institutes of Health. We are indebted to Dr. E. Forchielli from the Syntex Corporation, Palo Alto, CA, for supplying mestranol, and to Mrs. L. Andiric for her excellent technical assistance.
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