Abstract
Summary
In the liver of castrated rats a significant decrease of total folate coenzymes and, in particular, of 10-HCO-H4folate and H4folate was observed. Treatment with testosterone normalizes the folate content of these structures. The decrease in folate coenzymes is evident in the prostate but here too, hormone administration restores the normal folate content. Castration does not significantly alter the content or distribution of folate coenzymes in seminal vesicles.
We are indebted to Mr. Roberto Laffi for excellent technical assistance.
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