Abstract
Summary
Ovulation was produced on Day 25 in immature rats hypophysectomized just prior to the administration of from 3 to 30 IU of PMS on Day 22 plus injection of 7.5 or 10 IU of HCG in the afternoon of Day 24. However, the incidence of ovulation did not show the biphasic dose-response as reported previously in intact immature rats treated with the same amounts of PMS. Administration of PMS alone or PMS plus 5 IU HCG did not induce ovulation in hypophysectomized immature rats.
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