Abstract
Summary
High titers of transplantation antibodies, as measured by a hemagglutination test, were induced in Buffalo strain rats by repeated inoculations of a carcinogeninduced tumor maintained in Fischer-344 rats. This tumor grew in Buffalo rats immunosuppressed by X-irradiation and cortisone. When a gamma globulin fraction from pooled immune serum was injected intravenously into such tumor-bearing rats the antibody titer in blood declined more rapidly than in similar immunosuppressed rats without tumor transplants.
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