Abstract
Summary
A graded response of the baboon (P. cynocephalus), Cebus (C. apella) and marmoset (S. oedipus) monkeys to infection via the female genital tract with H. hominis type 2 was demonstrated. A subclinical disease with limited virus production and antibody response was noted in the baboons. All Cebus monkeys showed clinical evidence of genital infection, extensive virus excretion and antibody response. Whereas baboons and Cebus monkeys survived inoculation with H. hominis type 2, a generalized fatal infection was observed in the marmosets.
This study was funded in part by U.S. Public Health Service grants RR05519, RR00278, RR00361, RR00451 and contract NIH 69–93 and WHO grant Z2/181/27. Dr. Nahmias is supported in part by grant T-521 from the American Cancer Society.
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