Abstract
Summary
Serum antibodies to envelope antigens of A/Equi-2 virus were determined in persons of various ages with no known exposure to human A2/Hong Kong/68 virus. Antibody to neuraminidase and hemagglutinin antigens was observed predominantly in persons born before 1900. These results raise the possibility that A/Equi-2 influenza virus originated in the human host.
The authors thank Dr. David W. Alling for his review of this manuscript.
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