Abstract
Summary
Cell-to-cell spread of mumps virus infection to form plaques in HeLa cell monolayers was studied in the presence and absence of mumps virus hyperimmune antiserum in the overlay medium. Using two techniques of plaque detection, viral spread was found to be inhibited by the antiserum. When the antiserum was removed after 3–5 days, plaque formation resumed, but after 7 days of treatment very few plaques developed, indicating limited persistence of mumps virus in HeLa cells in the presence of external neutralizing antibody.
Get full access to this article
View all access options for this article.