Abstract
Summary
Pregnant rats were given a single injection of cysteine prior to exposure to chlorambucil on day 12 of gestation. This treatment caused a significant 6-fold increase in structurally normal surviving fetuses when compared to chlorambucil alone. The abnormal survivors demonstrated a less severe syndrome of anomalies that was not similar to the patterns of defects associated with chlorambucil treatment on other days of gestation.
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