Abstract
Summary
A preparation of a renal cell suspension system suitable for renin studies was utilized to investigate the in vitro effects of angiotensin which has previously been shown to influence renin production in vivo. The addition of angiotensin to the incubated samples caused a significant inhibition of renin production and release. It is suggested that the renin-inhibitory effect of angiotensin in the intact animal might be due, at least in part, to a direct chemical action on the renal cells.
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