Abstract
Summary
Coelomic parabiosis between mice differing in θ and/or H2 antigens was produced. Spleens of parabionts contained plaque-forming cells involved in the production of antibodies to the partner's antigens. No significant exchange of PFC between partners was noted. Sera of parabionts contained lytic antibodies to the partner's antigens as well as the animal's own antigens. Data supporting the mutual exchange of antibodies were presented. Evidence was obtained that anti-θ antibodies produced in one partner suppress immune response of the other partner whose circulation they entered.
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