Abstract
Summary
Cadmium (Cd) injected into rats at various time intervals in relation to antigen (Ag) (human gamma-globulin) administration was shown to have a diverse but significant effect on the immune response, as measured by the passive hemagglutination test. Cd2+ doses (0.6 mg/kg) initiated 14 and 7 days prior to Ag injection enhanced and suppressed antibody synthesis, respectively. Mechanisms of Cd involvement are discussed.
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