Abstract
Summary
Chlorite-oxidized oxyamylose (COAM), a polyacetal carboxylic acid, enhances the formation of antibodies against sheep red blood cells and influenza virus hemagglutinin. The effect was present only when the polymer was included in the immunizing antigen injection (intraperitoneally or intravenously), not when it was given at a time interval before the antigen or by a different administration route. This indicates that an interaction occurs at the site of injection between antigen and polymer, or between polymer and host cells which are involved in antigen processing.
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