Abstract
Summary
C3H/Bi weanling mice were grafted with skin taken from 4-week-old preleukemia, syngeneic mice (GPA virus system) which had been inoculated at birth with Gross passage A virus. Careful analysis of the tissues of the grafted weanlings (carried out after natural death of the animals) revealed a high incidence of thymus enlargement and a 100% incidence of disseminated lymphoma. This indicates that leukemogenesis was induced by means of skin transplantation in 100% of the weanling animals by the skin grafting of preleukemia skin.
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