Abstract
Summary
Chick blastoderms at H & H stage 8-8+ were cultured in vitro on 1 ml aliquots of medium containing either 50 or 100 μg of lysergic acid diethylamide. Following 20 hr incubation, drug-treated embryos failed to demonstrate any increase in mortality or growth-depressing effects. At both dose levels, however, disturbances were observed in fusion of the neural folds. A significant reduction in the mean number of somites per embryo was observed in embryos exposed to 50 μg of LSD.
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