Abstract
Summary
Stop-flow accumulation of 3H-PAH took place in cells and in lumina of proximal tubules. This strongly suggests that an active PAH is secreted by a “push” system, that is, the pump is located in the peritubular membrane of the cell. The rate of stop-flow accumulation of 3H-PAH in the distal tubules was over three times higher than in proximal tubules, while the concentration of 14C-inulin was decreasing in the distal tubules. Apparently there is a very active secretory pump for PAH between the proximal and distal convolutions, probably in the straight portion of the proximal tubule.
Get full access to this article
View all access options for this article.