Abstract
Summary
Bacterial vaccine, inoculated intraperitoneally into mice, stimulated a virus inhibitor in the serum with the characteristics of interferon. The inhibitor could be detected from 2 to 24 hr after inoculation. Serial inoculations on alternating days resulted in slightly lower, but still significant, interferon titers compared with that after the initial inoculation. One dose of vaccine was protective against intranasal inoculation with vesicular stomatitis virus, shown by extension of the survival time.
Get full access to this article
View all access options for this article.