Abstract
Summary
Thirty-six adult female rabbits were divided into four groups: controls, pregnant, Enovid-treated, and cholesterol-fed. Hypolipidemia was noted in pregnant rabbits and hyperlipidemia in cholesterol-fed rabbits. The nondialyzable aortic uronic contents of pregnant and Enovid-treated rabbits were not different from those of the controls, although previous histochemical studies on the same aortas revealed a marked reduction of alcian blue positive materials in the aortas of both pregnant and Enovid-treated rabbits. This false reduction may be the result of qualitative changes of aortic AMPS during pregnancy; these changes are very different from the quantitative increases found in atherosclerotic aortas. The latter showed no loss of stain with alcian blue dye.
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