Abstract
Summary
Dietary pyridoxal deficiency causes extensive changes, mostly reductions, in the amino acid content of the liver and kidneys, and to a lesser extent, the brain and heart. Treatment of pyridoxal-deficient rats with intraperitoneal decaborane (20 mg/kg) tended to accentuate the changes induced by pyridoxal deficiency. The data support the suggestion that boron hydrides (borane) are effective inhibitors of pyridoxal-dependent enzyme systems in vivo. The data indicate that other enzyme systems are also inhibited by boron hydrides.
Get full access to this article
View all access options for this article.