Abstract
Summary
Hyperthyroidism was induced in male, albino rats by subcutaneous injection of T3 daily for 2 weeks. The day following the last injection, groups of control and experimental animals were killed; the hearts were removed, weighed, and the average amount of cardiac hypertrophy was determined. The hearts were then partitioned and the ventricles were weighed separately. To determine when the hearts returned to normal size, groups of rats were killed at about 5-day intervals up to 35 days. The data were subjected to linear regression analysis. It was observed that the hearts returned to normal size in 13 days; this also held approximately for each ventricle despite the fact that the right ventricle was hypertrophied significantly more, proportionally, than the left ventricle.
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