Abstract
Summary
These studies illustrate the applicability of a tracheal organ culture system for the study of Mycoplasma pneumoniae infection at the cellular level. The results of immunofluorescence and electron microscopy indicate an intimate association of M. pneumoniae and the ciliated epithelial cell membrane. While M. pneumoniae appeared able to break down terminal bars and enter the intercellular spaces no evidence of intracellular localization was seen. These findings provide additional insight into the pathogenicity of M. pneumoniae.
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