Abstract
Conclusion
Two attenuated vaccine strains of rubella virus still retain their ability to grow in monolayer cultures of nonrheumatoid synovial cells, and by extension probably multiply within the synovial membrane of those recipients who develop arthritis post-vaccination. The growth characteristics of rubella in cultured synovial cells may reflect the degree of attenuation vis-à-vis growth in synovial membranes, and perhaps could be used to select strains of virus which would be unlikely to cause synovitis following immunization.
Get full access to this article
View all access options for this article.