Abstract
Summary
1. Two protein polysaccharide fractions. PPL-2 and PPL-3, were isolated from the costal cartilage of rat, 6 months, 1 and 2 years old.
2. The PPL-3 sedimented as a single component in the samples prepared from 2-year-old rats. In contrast, the PPL-2 from 2-year-old rats and PPL-2 and PPL-3 from 6-months- and 1-year-old rats were heterogeneous.
3. The chemical compositions (g/g of dried wt) protein: uronic acid: hexose: hexosamine are 0.324: 0.221 :0.054:0.248 and 0.121:0.270:0.061:0.272 for PPL-2 and PPL-3, respectively. Ninety-five % of the hexosamine was galactosamine in both preparations.
4. The amino acid composition of rat costal cartilage is compared with that of human costal cartilage and bovine nasal cartilage.
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