Abstract
Summary
Diuresis following gastric gavage of water was examined in germfree and conventional rats. Germfree rats began to excrete urine 1 hr later than the conventional group and the volume of urine excreted by the germfree animals was less than excreted by the conventional group. Saline excretion patterns were the same for the two groups of animals. When 4% glucose was administered subcutaneously, excretion patterns were similar to that obtained following gastric gavage of water except that the onset of excretion was delayed 2 hr in the germfree as compared with the conventional group.
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