Abstract
Summary
A number of substances, most of them normal intermediates of red cell glucose metabolism, were tested for their effect on the shift in the oxygen dissociation curve produced by 2,3-diphosphoglycerate. None of the substances tested, with the exception of ATP and pyridoxal phosphate had any effect on the dissociation curve, either in the presence or absence of 2,3-DPG, ATP and pyridoxal phosphate caused a rightward displacement of the dissociation curve, but this occurred both in the presence and absence of 2,3-DPG and was considered to be simply an additive effect.
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