Abstract
Summary
During continuous infusion of dyes into rats, rapid injection of BSP produced a transient depression in bile flow rate, whereas rapid injection of the synthetically conjugated moiety (BSP-GSH) produced no change in bile flow. Rapid injection of DBSP, a BSP analog excreted without biotransformation, produced a less marked change in bile flow. These findings suggest that colligative, or other properties specific to unconjugated dyes, may affect bile flow.
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