Abstract
Summary
The simultaneous cellular antibody response to two antigens was studied in guinea pigs made hyperimmune to a glutaraldehyde-treated antigen mixture of egg albumin and human gamma globulin. In such animals varying numbers of antibody-forming cells could be detected in the lungs, liver, kidneys, and adrenal glands. The lungs and liver appeared to be major sites of antibody synthesis. If these cells are the progeny of potential antibody-forming cells stimulated in situ or if these cells were stimulated in lymphoid organs and filtered from the circulation is not known.
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