Abstract
Summary
The blood pressure response of the rat to the ganglionic stimulant 1,1-dimethylphenylpiperazinium iodide (DMPP) was much less sensitive than that of the cat. Acute bilateral adrenalectomy did not diminish the pressor response to DMPP in the rat. Bretylium or guanethidine completely or virtually abolished the pressor response produced by DMPP. It was concluded that, in the rat, the adrenals appear not to play a role in the pressor response produced by DMPP.
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