Abstract
Summary
THA administered subcutaneously caused a dose-related diuresis in rats. This diuretic response was probably not due to a muscarinic action of THA, as the diuresis was not blocked by atropine. Preliminary experiments in the dog and the chicken indicate that in these species there was little if any direct renal effect. The diuretic response to THA in rats does not appear to involve release of a pituitary hormone since hypophysectomy did not abolish the diuretic effect of THA.
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