Abstract
Summary
An interferon-stimulating compound, pyran copolymer, has been shown to protect adult thymectomized mice treated with antilymphocyte serum from Rauscher virus-induced leukemia without affecting their unresponsiveness to skin homografts. Although the mechanisms of this protection are uncertain, severely immunosuppressed hosts have been shown to be capable of producing interferon following pyran copolymer challenges. The potential usefulness of these agents in the prophylaxis against virus diseases and possible virus oncogenesis in immunosuppressed humans is discussed.
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