Maximal Hepatic Excretion of Bilirubin in Sheep 1

Abstract

Summary

The maximal excretory rate of bilirubin from plasma into bile is similar in sheep to values reported for other species. The average hepatic excretory maximum for bilirubin was 47 μg/100 g/min. An average concentration maxima of 17 mg of bilirubin/ ml of bile was observed. Hepatic excretion of bilirubin into ovine bile is limited by a concentration maximum and the rate at which conjugated bilirubin may be transported from the hepatocyte into bile.